Activating Transcription Factor 3 and the Nervous System
نویسندگان
چکیده
منابع مشابه
Activating Transcription Factor 3 and the Nervous System
Activating transcription factor 3 (ATF3) belongs to the ATF/cyclic AMP responsive element binding family of transcription factors and is often described as an adaptive response gene whose activity is usually regulated by stressful stimuli. Although expressed in a number of splice variants and generally recognized as a transcriptional repressor, ATF3 has the ability to interact with a number of ...
متن کاملExpression and Clinical Significance of Activating Transcription Factor 3 in Human Breast Cancer
Objective(s): Breast cancer is the most common type of cancer among women worldwide. This study investigated the expression and clinical significance of activating transcription factor 3 (ATF3) in human breast cancer and its relationship with the clinical outcome of breast cancer. Materials and Methods : ATF3 expressions were detected in 114 primary breast cancer tissues and ...
متن کاملexpression and clinical significance of activating transcription factor 3 in human breast cancer
objective(s): breast cancer is the most common type of cancer among women worldwide. this study investigated the expression and clinical significance of activating transcription factor 3 (atf3) in human breast cancer and its relationship with the clinical outcome of breast cancer. materials and methods : atf3 expressions were detected in 114 primary breast cancer tissues and 114 adjacent norm...
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Activating transcription factor 3 (ATF3) is a common stress sensor, and its rapid induction by cellular stresses (e.g. DNA damage) is crucial for cells to mount appropriate responses (e.g. activating the tumor suppressor p53) and maintain homeostasis. Although emerging evidence suggests that dysregulation of ATF3 contributes to occurrences of human diseases including cancer, the mechanism(s) by...
متن کاملATF2 (activating transcription factor 2)
Other names: CREB1, CRE-BP1, CREB2, CREBP1, HB16, MGC111558, TREB7 HGNC (Hugo): ATF2 Location: 2q31.1 Note ATF2 (2q31.1) is sometimes confused with CREB1 (2q33.3), because an alias of ATF2 is CREB1, also because they are both CREB-related proteins, a family of transcription factors of the bZIP superfamily, whose members have the ability to heterodimerize with each other, and, finally, because C...
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ژورنال
عنوان ژورنال: Frontiers in Molecular Neuroscience
سال: 2012
ISSN: 1662-5099
DOI: 10.3389/fnmol.2012.00007